Lyrica is anticonvulsant that has an anti-epileptic effect and effectively diminishes the impulse in the brain that causes seizures. Lyrica is found to be effective in controlling seizures. It is also used to diminish the agony or discomfort caused by nerve damage in people with diabetic peripheral neuropathy, post-herpetic neuralgia, or neuropathic pain allied with the injury of the spinal cord. Lyrica has pain relieving effects and used to provide relief from the pain all over the body. Lyrica contains a generic drug called Pregabalin.
Pregabalin modulates the activity of calcium channel and reduces the calcium-dependent release of several neurotransmitters. It lowers down the interneuron communication and delays the impulse conduction in the brain. Ultimately, it reduces the nerve pain and seizures.
Lyrica should not be consumed by those patients who are hypersensitive to Lyrica or its other components. Before using Lyrica, patients have to discuss with their healthcare professional about their medical conditions such as depression, mood problems, or suicidal thoughts, kidney disorder, heart failure, bleeding disorder, drug abused conditions, and angioedema.
Sometimes Lyrica can show drug interactions with other medicines when they are administered together such as Angiotensin-converting enzyme (ACE) inhibitors, Rosiglitazone, Pioglitazone, Lorazepam, Oxycodone, morphine, codeine, anti antihistamines. These drugs alter the therapeutic efficacy of Lyrica.
Lyrica capsule is commercially available in different dosage strengths is 25 mg, 50 mg, 75 mg, 100 mg, 150 mg, 200 mg, 225 mg and 300 mg. If you suffer from neuropathic pain associated with diabetic peripheral neuropathy then you should start with a dose of 50 mg of Lyrica three times a day (150 mg of Lyrica per day) and the dose may be increased up to 300 mg of Lyrica in a day within one week. In the case of postherpetic neuralgia, you can take 75 to 150 mg of Lyrica two times a day or 50 to 100 mg of Lyrica three times a day (150 to 300 mg/day. In the case of epileptic seizures, you have to take 150 mg to 600 mg of Lyrica as adjunctive therapy to manage partial onset seizures in adults. In the treatment of fibromyalgia, you have to start with 75 mg of Lyrica orally two times a day and the dose may be enhanced up to 150 mg of Lyrica within one week on the basis of efficacy and tolerability. The recommended dose of Lyrica in the management of fibromyalgia is 300 to 450 mg/ day. If you suffer from neuropathic pain associated with spinal cord injury, then you have to take 150 to 600 mg of Lyrica in a day.
A patient can experience some undesired effects while using Lyrica such as headache, nausea, vomiting, drowsiness, dizziness, dry mouth, speech problems, edema, weakness, lack of concentration, constipation and lack of coordination.
The use of Lyrica may impair your thinking ability, so don’t drive a car or operate any machinery. You should not recommend this medicine to the patient under 18 years of age. If you want to discontinue this medicine, then reduce the dose of Lyrica over the course of a week. Lyrica should not be recommended for breastfeeding mothers.
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